Jigsaw

Criminal Edgar Munsen is pursued by the police onto a rooftop, where he activates a triggering mechanism before being shot non-fatally by Police Detective Halloran and his fellow officers.

Five people are held captive in a barn, each with a metal noose around their neck. A tape recording from John Kramer explains they must give a sacrifice of blood and will need to confess their sins. The chains begin pulling them towards a wall of buzzsaws. Four manage to survive by cutting themselves on the blades as an offering of blood, but one man who was unconscious during the majority of the game appears to die.

The next test divulges that group member Carly caused the death of an asthmatic woman by stealing her purse, which had her emergency inhaler inside. To save the others from being hanged, she must inject herself with one of the three needles- one containing an antidote to a poison in her system, one a saline solution, and one a potent acid. Volatile group member Ryan eventually stabs Carly with all three to save himself, melting her face and killing her. Read more on Wikipedia.